Recent Publications

For more publications:

  1. J Li, W Wang , Y Zhang , M Cieślik, J Guo J, M Tan, MD Green, W Wang, H Lin, W Li, S Wei, J Zhou, G Li, X Jing, L Vatan, L Zhao, B Bitler, R Zhang, KR Cho, Y Dou, I Kryczek, TA Chan, D Huntsman, AM Chinnaiyan, W Zou. Epigenetic driver mutations in ARID1A shape cancer immune phenotype and immunotherapy. J Clin Invest (2020).
  2. W. Zou, Y. M. Shah, A PHD in immunosuppression: oxygen-sensing pathways regulate immunosuppressive Tregs. J Clin Invest 130, 3524-3526 (2019).
  3. Q. Zhang, M. D. Green, X. Lang, J. Lazarus, J. D. Parsels, S. Wei, L. A. Parsels, J. Shi, N. Ramnath, D. R. Wahl, M. Pasca di Magliano, T. L. Frankel, I. Kryczek, Y. L. Lei, T. S. Lawrence, W. Zou, M. A. Morgan, Inhibition of ATM Increases Interferon Signaling and Sensitizes Pancreatic Cancer to Immune Checkpoint Blockade Therapy. Cancer Res 79, 3940-3951 (2019).
  4. C. Y. Yu, J. X. Han, J. Zhang, P. Jiang, C. Shen, F. Guo, J. Tang, T. Yan, X. Tian, X. Zhu, D. Ma, Y. Hu, Y. Xie, W. Du, M. Zhong, J. Chen, Q. Liu, D. Sun, Y. Chen, W. Zou, J. Hong, H. Chen, J. Y. Fang, A 16q22.1 variant confers susceptibility to colorectal cancer as a distal regulator of ZFP90. Oncogene, (2019).
  5. W. Wang, J. R. Liu, W. Zou, Immunotherapy in Ovarian Cancer. Surg Oncol Clin N Am 28, 447-464 (2019).
  6. W. Wang, M. Green, J. E. Choi, M. Gijon, P. D. Kennedy, J. K. Johnson, P. Liao, X. Lang, I. Kryczek, A. Sell, H. Xia, J. Zhou, G. Li, J. Li, W. Li, S. Wei, L. Vatan, H. Zhang, W. Szeliga, W. Gu, R. Liu, T. S. Lawrence, C. Lamb, Y. Tanno, M. Cieslik, E. Stone, G. Georgiou, T. A. Chan, A. Chinnaiyan, W. Zou, CD8(+) T cells regulate tumour ferroptosis during cancer immunotherapy. Nature 569, 270-274 (2019).
  7. Zhong, J. Chen, Z. Ge, X. Li, X. Chen, Y. Cui, Y. Chen, W. Zou, H. Chen, J. Hong, J. Y. Fang, LncRNA GLCC1 promotes colorectal carcinogenesis and glucose metabolism by stabilizing c-Myc. Nat Commun 10, 3499 (2019).
  8. T. Maj, W. Zou, Rewiring regulatory T cells for tumour killing. Nat Biomed Eng 3, 766-767 (2019).
  9. Liu X, Z. E., Li H, Lesch CA, Dunbar J, Bousley D, Zou W, Hu X, Carter LL. RORγ Agonists Enhance the Sustained Antitumor Activity through Intrinsic Tc17 Cytotoxicity and Tc1 Recruitment. Cancer Immunol Res 7, 1054-1063, doi:10.1158/2326-6066.CIR-18-0714 (2019).
  10. J. Lazarus, Y. Akiska, M. Perusina Lanfranca, L. Delrosario, L. Sun, D. Long, J. Shi, H. Crawford, M. P. Di Magliano, W. Zou, T. Frankel, Optimization, Design and Avoiding Pitfalls in Manual Multiplex Fluorescent Immunohistochemistry. J Vis Exp, (2019).
  11. J. Lazarus, M. D. Oneka, S. Barua, T. Maj, M. P. Lanfranca, L. Delrosario, L. Sun, J. J. Smith, M. I. D'Angelica, J. Shia, J. M. Fang, J. Shi, M. P. Di Magliano, W. Zou, A. Rao, T. L. Frankel, Mathematical Modeling of the Metastatic Colorectal Cancer Microenvironment Defines the Importance of Cytotoxic Lymphocyte Infiltration and Presence of PD-L1 on Antigen Presenting Cells. Ann Surg Oncol 26, 2821-2830 (2019).
  12. X. Lang, M. D. Green, W. Wang, J. Yu, J. E. Choi, L. Jiang, P. Liao, J. Zhou, Q. Zhang, A. Dow, A. L. Saripalli, I. Kryczek, S. Wei, W. Szeliga, L. Vatan, E. M. Stone, G. Georgiou, M. Cieslik, D. R. Wahl, M. A. Morgan, A. M. Chinnaiyan, T. S. Lawrence, W. Zou, Radiotherapy and immunotherapy promote tumoral lipid oxidation and ferroptosis via synergistic repression of SLC7A11. Cancer Discov, (2019).
  13. M. P. Lanfranca, Y. Zhang, A. Girgis, S. Kasselman, J. Lazarus, I. Kryczek, L. Delrosario, A. Rhim, L. Koneva, M. Sartor, L. Sun, C. Halbrook, H. Nathan, J. Shi, H. C. Crawford, M. Pasca di Magliano, W. Zou, T. L. Frankel, Interleukin 22 Signaling 28 Regulates Acinar Cell Plasticity to Promote Pancreatic Tumor Development in Mice. Gastroenterology, (2019).
  14. S. Bishu, M. El Zaatari, A. Hayashi, G. Hou, N. Bowers, J. Kinnucan, B. Manoogian, M. Muza-Moons, M. Zhang, H. Grasberger, C. Bourque, W. Zou, P. D. R. Higgins, J. R. Spence, R. W. Stidham, N. Kamada, J. Y. Kao, CD4+ Tissue-resident Memory T Cells Expand and Are a Major Source of Mucosal Tumour Necrosis Factor alpha in Active Crohn's Disease. J Crohns Colitis 13, 905-915 (2019).
  15. S. Bishu, G. Hou, M. El Zaatari, S. R. Bishu, D. Popke, M. Zhang, H. Grasberger, W. Zou, R. W. Stidham, P. D. R. Higgins, J. R. Spence, N. Kamada, J. Y. Kao, Citrobacter rodentium Induces Tissue-Resident Memory CD4(+) T Cells. Infect Immun 87, (2019).
  16. Wu YM, Cieslik M, Lonigro RJ, et al. Inactivation of CDK12 Delineates a Distinct Immunogenic Class of Advanced Prostate Cancer. Cell 2018;173:1770-1782 e14.
  17. W. Wang, W. Zou, J. R. Liu, Tumor-infiltrating T cells in epithelial ovarian cancer: predictors of prognosis and biological basis of immunotherapy. Gynecol Oncol 151, 1-3 (2018).
  18. J. Lazarus, T. Maj, J. J. Smith, M. Perusina Lanfranca, A. Rao, M. I. D'Angelica, L. Delrosario, A. Girgis, C. Schukow, J. Shia, I. Kryczek, J. Shi, I. Wasserman, H. Crawford, H. Nathan, M. Pasca Di Magliano, W. Zou, T. L. Frankel, Spatial and phenotypic immune profiling of metastatic colon cancer. JCI Insight 3, (2018).
  19. M. P. Lanfranca, J. Lazarus, X. Shao, H. Nathan, M. P. Di Magliano, W. Zou, M. Piert, T. L. Frankel, Tracking Macrophage Infiltration in a Mouse Model of Pancreatic Cancer with the Positron Emission Tomography Tracer [11C]PBR28. J Surg Res 232, 570-577 (2018).